Recurrent Respiratory Papillomatosis (RRP): Benign Lesions on the Vocal Cords Caused by HPV

Recurrent respiratory papillomatosis (RRP) is a condition characterized by benign tumors that develop on the vocal cords and respiratory tract due to human papillomavirus (HPV). These lesions have a tendency to recur and may cause symptoms such as hoarseness, difficulty breathing, and impaired speech.

Symptoms of RRP

  • Hoarseness and voice changes (Most common symptom)
  • Shortness of breath (In advanced cases)
  • Difficulty speaking
  • Sensation of fullness in the throat
  • Changes in crying voice and breathing issues in children

How Is Recurrent Respiratory Papillomatosis Treated?

  • Microlaryngeal surgery: Removal of papillomas without damaging the vocal cords.
  • Laser or cold knife surgery: Used to precisely excise the papillomas.
  • Adjuvant therapies: Interferon, bevacizumab (anti-angiogenic treatments), and HPV vaccines may support the treatment.
  • Regular monitoring: Due to its recurrent nature, patients should be followed up regularly.

Conclusion

RRP is a manageable condition with early diagnosis and regular treatment, but it has a risk of recurrence. If symptoms such as hoarseness or breathing difficulties are noticed, an ENT specialist should be consulted for early diagnosis.

Prof. Dr. Elif Aksoy
ENT Specialist – Voice and Respiratory Disorders

Prof. Dr. Elif Aksoy
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