Swallowing Disorders: Causes, Symptoms, and Treatment Methods

Swallowing disorder (dysphagia) is a condition that prevents food and liquids from being transported safely and effectively from the mouth to the stomach. Swallowing is a complex process consisting of three phases: oral, pharyngeal, and esophageal. A dysfunction in any of these phases may lead to dysphagia. Swallowing difficulties can severely impact quality of life and may cause serious complications such as malnutrition, dehydration, and aspiration pneumonia.

Causes of Swallowing Disorders

Swallowing disorders often arise from neurological, musculoskeletal, structural, or functional disorders. Primary causes include:

Neurological Causes

  • Stroke: Damage to the areas of the brain that control swallowing can disrupt the synchronization of pharyngeal and esophageal muscles.
  • Parkinson’s Disease: Motor control issues may delay the swallowing reflex and increase aspiration risk.
  • Amyotrophic Lateral Sclerosis (ALS): Muscle weakness and lack of coordination may result in dysphagia.
  • Dementia and Alzheimer’s Disease: Cognitive decline may impair the swallowing reflex and compromise safe swallowing.

Muscle and Connective Tissue Disorders

  • Myasthenia Gravis: Causes muscle weakness that may hinder the swallowing process.
  • Scleroderma: Hardening of the esophageal muscles may lead to swallowing difficulties.
  • Myotonic Dystrophies: Affect muscle relaxation and contraction, disrupting the swallowing process.

Structural and Mechanical Causes

  • Esophageal Strictures and Tumors: Narrowing of the esophagus can hinder food passage.
  • Gastroesophageal Reflux Disease (GERD): Chronic reflux can cause inflammation and narrowing of the lower esophagus, leading to dysphagia.
  • Head and Neck Cancers: Post-surgical or post-radiotherapy anatomical deformities and muscle dysfunctions may occur.
  • Laryngopharyngeal Reflux: Acid reflux may irritate the pharyngeal muscles and impair the swallowing reflex.

Symptoms and Diagnostic Methods

Symptoms of dysphagia vary depending on the severity and underlying cause. Common symptoms include:

  • Pain while swallowing (odynophagia)
  • Sensation of food sticking in the throat
  • Coughing, choking, or voice changes during or after eating
  • Regurgitation of food or liquid through the nose (nasal regurgitation)
  • Weight loss, signs of malnutrition, and dehydration
  • Recurring respiratory infections and aspiration pneumonia

Diagnostic Methods

Primary diagnostic tools for dysphagia include:

  • Video-Fluoroscopic Swallow Study (VFSS): Radiologically evaluates the detailed swallowing process.
  • Fiberoptic Endoscopic Evaluation of Swallowing (FEES): Examines pharyngeal and laryngeal functions using a flexible endoscope.
  • Manometry: Measures esophageal muscle movements using pressure sensors.
  • Barium Swallow Test: Assesses the anatomical and functional integrity of the esophagus.

Treatment Methods

The management of dysphagia depends on the underlying cause, the patient’s overall health, and the level of swallowing function. Treatment options include:

Conservative Treatments

  • Diet Modification: Adjusting food consistency according to the patient’s individual needs (e.g., pureed or jelly-like foods)
  • Swallowing Therapy: Applied by speech-language pathologists using compensatory techniques and maneuvers to strengthen swallowing function.
  • Head and Neck Positioning: Changing head and neck positions to reduce aspiration risk during swallowing.

Medical and Pharmacological Treatments

  • Dysphagia due to laryngopharyngeal reflux: Managed using proton pump inhibitors (PPI) or H2 receptor blockers to control stomach acid.
  • Neurological disorders: Medications that support neural transmission may be used.

Surgical and Interventional Treatments

  • Esophageal Dilation: Balloon or bougie dilation is used to treat esophageal strictures.
  • Botulinum Toxin Injection: Used in cases of hyperactive esophageal sphincters causing dysphagia.
  • Gastrostomy (PEG – Percutaneous Endoscopic Gastrostomy): A feeding tube is placed directly into the stomach for patients with severe dysphagia at high aspiration risk.
  • Surgical Resection: May be necessary in dysphagia caused by tumors or anatomical abnormalities.

Conclusion and Clinical Significance

Swallowing disorders significantly impact patients’ quality of life by causing respiratory infections due to aspiration, malnutrition, and dehydration. Early diagnosis and appropriate treatment strategies can reduce aspiration risk, improve nutritional safety, and maintain patients’ functional independence. Especially in elderly and neurologically impaired patients, regular follow-up and multidisciplinary approaches are crucial to prevent dysphagia-related complications.

Prof. Dr. Elif Aksoy
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